维百奥生物代理ProQinase品牌全系列产品
ProQinase GmbH公司于2001年成立，是弗莱堡肿瘤生物学中心（欧洲同类型规模最大的私立医疗机构之一）的全资子公司。致力于为癌症治疗领域提供靶向蛋白激酶的创新药物研发服务。公司独有的整合性蛋白激酶技术平台覆盖临床前药物研发全周期，其服务范围涵盖从先导化合物筛选到动物体内概念验证的全流程，提供包括标准化和定制化解决方案的广泛服务组合。公司产品线包括激酶相关产品、定制蛋白质生产、检测试剂盒、表观遗传和其他产品。
▍ProQinase产品线
● 激酶相关产品：Reaction Biology提供广泛的重组激酶产品，适用于开发激酶活性测定。除了活性激酶蛋白(包括脂质激酶和蛋白激酶)外，还提供激酶蛋白变体和激酶底物。可以根据对活性激酶和其他潜在药物靶点的具体要求进行定制的重组激酶蛋白生产。重组激酶可以等分试样、现成或批量购买。
● 定制蛋白质生产：提供蛋白质生产和检测开发服务，包括小规模或大规模定制蛋白质生产、检测开发和优化/验证、酶测试、底物测试和激活剂/抑制剂测试。
● 检测试剂盒：提供BromoMELT检测试剂盒。
● 表观遗传相关产品：提供所有表观遗传相关产品，包括甲基转移酶蛋白、甲基转移酶底物、阅读结构域蛋白、脱乙酰化酶蛋白、去甲基化酶蛋白、DNA修复蛋白、IDH蛋白、PARP蛋白、检测试剂盒和表观遗传抑制剂。
● 其他产品：包括Ras相关蛋白、NQO蛋白质、细胞凋亡蛋白、NUDIX和核苷酸池卫生蛋白、杂项蛋白质、脱亚胺酶蛋白和SARS-CoV-2相关蛋白。
▍ProQinase部分产品列表
| 品名 | 货号 | 产品描述 | 规格 |
| ProQinase™ ABL1 | 0992-0000-1 | human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 E255K | 0924-0000-1 | human, internal fragment, E255K mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 F317I | 0989-0000-1 | human, internal fragment, F317I mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 G250E | 0925-0000-1 | human, internal fragment, G250E mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 H396P | 0991-0000-1 | human, internal fragment, H396P mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 M351T | 0990-0000-1 | human, internal fragment, M351T mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 Q252H | 0926-0000-1 | human, internal fragment, Q252H mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 T315I | 0757-0000-1 | human, internal fragment, T315I mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL1 Y253F | 0927-0000-1 | human, internal fragment, Y253F mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ABL2 | 1548-0000-1 | human, N-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ACK1 | 0493-0000-1 | human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ACVR1 | 0372-0000-1 | human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AKT1 | 1379-0000-2 | human, full length, activated, GST fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AKT1 aa106-480 | 0132-0000-2 | human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AKT2 | 1577-0000-1 | human, full length, activated, GST fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AKT2 aa107-481 | 0276-0000-2 | human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AKT3 | 1578-0000-1 | human, full length, activated, GST fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AKT3 aa106-479 | 0436-0000-2 | human, C-terminal fragment, GST-HIS fusion protein, activated, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK | 1176-0000-1 | human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK C1156Y | 1177-0000-1 | human, internal fragment, C1156Y mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK F1174L | 1178-0000-1 | human, internal fragment, F1174L mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK F1174S | 1179-0000-1 | human, internal fragment, F1174S mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK G1202R | 1369-0000-1 | human, internal fragment, G1202R mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK L1196M | 1180-0000-1 | human, internal fragment, L1196M mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ALK R1275Q | 1181-0000-1 | human, internal fragment, R1275Q mutation, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AMPKalpha1 | 0289-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AMPKalpha1 aa1-312 | 0383-0000-1 | human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ARK5 | 0300-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ASK1 | 1998-0000-1 | human, internal fragment, GST-HIS fusion protein, expressed in Sf9 insect cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ ASK2 | 2017-0000-1 | human, internal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AuroraA | 0166-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AuroraB | 0190-0000-1 | human, full-length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AuroraC | 0315-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ AXL | 0525-0000-1 | human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BLK | 0448-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BMPR1A | 1655-0000-1 | human, C-terminal fragment, untagged, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BMPR1B | 1667-0000-1 | human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BRAF | 0403-0000-1 | human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BRK | 0181-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BRSK2 | 1524-0000-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ BTK | 0772-0000-2 | human, full length, GST fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDC42BPB | 0382-0000-1 | human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDC7/DBF4 | 1513-1516-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK1/CycA1 | 0134-2122-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK1/CycA2 | 0134-0054-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK1/CycB1 | 0134-0135-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK1/CycE1 | 0134-0055-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK1/CycE2 | 0134-2123-1 | human, full length, GST-HIS fusion protein, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK1/CycO | 0134-2135-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
| ProQinase™ CDK10/CycQ | 1527-1822-1 | human, full length, GST-HIS fusion proteins, expressed in Sf9 cells | 10 μg, 100 μg, 1 mg, bulk |
