产品名称 | Zileuton - 50 mg(rPeptide) |
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目录号 | N-3023-2 |
别名 | Zileuton |
外观 | N/A |
分子量 | 236.3 |
CAS | N/A |
溶解度 | N/A |
存储条件 | -20℃ |
保存时间 | 见标签 |
备注1 | N/A |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
N-3023-2 | 50 mg | 请咨询客服 | 请咨询客服 |
品名: Zileuton
货号: N-3023-2
规格: 50 mg
品牌:rPeptide
储存温度:-20℃
序列:N/A
来源:N/A
描述:Reversible inhibitor of 5-Lipoxygenase (IC50 = 500 nM in RBL-1 cells and 300 nM rat PMNLs)[1]. It also inhibited leukotriene B4 biosynthesis (IC50's = 400nM rat PMNL, 400nM human PMNL)[1]. Zileuton suppressed prostaglandin biosynthesis via interference with arachidonic acid release in macrophages independent of 5-LO inhibition (IC50 = 13 μM PGE2 inhibition in LPS-stimulated whole blood)[2]. Restores memory impairments and reverses amyloid and tau pathology in an Alzheimer’s mouse model[3].
分子量:236.3
纯度:>98%