产品名称 | Tolcapone - 10 mg(rPeptide) |
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目录号 | N-3007-1 |
别名 | Tolcapone |
外观 | N/A |
分子量 | 273.2 |
CAS | N/A |
溶解度 | N/A |
存储条件 | -20℃ |
保存时间 | 见标签 |
备注1 | N/A |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
N-3007-1 | 10 mg | 请咨询客服 | 请咨询客服 |
品名: Tolcapone
货号: N-3007-1
规格: 10 mg
品牌:rPeptide
储存温度:-20℃
序列:N/A
来源:N/A
描述:Catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes[1]. Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity[2]. Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo[3]. Inhibits O-methylation of exogenous polyphenols such as EGCG[4]. Cell permeable. Orally bioavailable.
分子量:273.2
纯度:>98%