产品名称 | SB-225022 - 5 mg(rPeptide) |
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目录号 | N-3016-1 |
别名 | SB-225022 |
外观 | N/A |
分子量 | 352.14 |
CAS | N/A |
溶解度 | N/A |
存储条件 | -20℃ |
保存时间 | 见标签 |
备注1 | N/A |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
N-3016-1 | 5 mg | 请咨询客服 | 请咨询客服 |
品名: SB-225022
货号: N-3016-1
规格: 5 mg
品牌:rPeptide
储存温度:-20℃
序列:N/A
来源:N/A
描述:Potent and selective CXCR2 receptor antagonist (IC50 = 22 nM). Displays >150-fold selectivity over CXCR1 receptors[1]. Induces apoptosis in both wild-type and p53-deficient ovarian cancer cells (OVCA) via p53 activation and by inducing mitotic catastrophe[2]. Blocks IL-8-mediated cellular effects such as oxidative stress-induced cellular senescence3 and neutrophil chemotaxis[1]. Inhibits HIV replication in lymphocytes and macrophages[4]. Inhibits endothelial activation and leukocyte recruitment to cerebral microvessels during neuroinflammation[5].
分子量:352.14
纯度:>98%