产品名称 | ISRIB - 25mg(rPeptide) |
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目录号 | N-1539-2 |
别名 | ISRIB |
外观 | N/A |
分子量 | N/A |
CAS | N/A |
溶解度 | N/A |
存储条件 | -20℃ |
保存时间 | 见标签 |
备注1 | N/A |
备注2 |
目录号 | 规格 | 价格 | 库存状态 | |
N-1539-2 | 25mg | 请咨询客服 | 请咨询客服 |
品名: ISRI
货号: BN-1539-2
规格: 25mg
品牌:rPeptide
储存温度:-20℃
序列:N/A
来源:N/A
描述:Integrated stress response inhibitor. Potently reverses the effects of initiation factor 2α (eIF2α) phosphorylation, IC50=5 nM[1]. Enhances spatial and fear-associated learning in mice and enhances cognitive function1,[2]. Mechanism of action involves activation of eiF2β[3]. Suppresses ER stress-induced inflammatory gene expression[4]. Potently attenuates amyloid β-induced neuronal cell death (1[2].5-25 nM) with no effect on amyloid β production[5]. Reverses hippocampal-dependent cognitive deficits induced by traumatic brain injury in two different injury mouse models[6].
分子量:N/A
纯度:N/A