| 产品名称 | FPS-ZM1 - 5mg（rPeptide） |
|---|---|
| 目录号 | N-1635-1 |
| 别名 | FPS-ZM1 |
| 外观 | N/A |
| 分子量 | 327.1 |
| CAS | N/A |
| 溶解度 | N/A |
| 存储条件 | -20℃ |
| 保存时间 | 见标签 |
| 备注1 | N/A |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| N-1635-1 | 5mg | 请咨询客服 | 请咨询客服 |
品名: FPS-ZM1
货号: N-1635-1
规格: 5mg
品牌：rPeptide
储存温度：-20℃
序列：N/A
来源：N/A
描述：A high-affinity RAGE (Receptor for Advanced Glycation End products) receptor antagonist (Ki = 25 nM). It lowers levels of Aβ via binding to the V domain of RAGE and can block multiple mechanisms of Aβ40- and Aβ42-induced cellular stress in RAGE-expressing brain endothelium, neurons and microglia in vitro and in vivos1,[2]. In a rat model of intracerebral hemorrhage, FPS-ZM1 attenuates blood-brain barrier and white matter fiber damage[3]. It ameliorates inflammatory damage after acute intracerebral hemorrhage via downstream blockade of high mobility box-1(HMGB1) signaling[4]. Attenuates AGE-induced neuroinflammation and oxidative stress in rat microglia[5]. BBB permeable.
分子量：327.1
纯度：>98%
