| 产品名称 | ANA-12 - 5 mg（rPeptide） |
|---|---|
| 目录号 | N-3031-1 |
| 别名 | ANA-12 |
| 外观 | N/A |
| 分子量 | 407.5 |
| CAS | N/A |
| 溶解度 | N/A |
| 存储条件 | -20℃ |
| 保存时间 | 见标签 |
| 备注1 | N/A |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| N-3031-1 | 5 mg | 请咨询客服 | 请咨询客服 |
品名: ANA-12
货号: N-3031-1
规格: 5 mg
品牌：rPeptide
储存温度：-20℃
序列：N/A
来源：N/A
描述：TrkB receptor antagonist. Binds to two distinct receptor sites preventing activation by BDNF non-competitively, IC50 = 4[5].6 nM and 4[1].1 μM for the high and low affinity sites respectively. Systemic administration to adult mice decreased TrkB activity in the brain without affecting neuronal survival or altering TrkA and TrkC functions. Displays antidepressant and anxiolytic properties in mouse models after systemic administration[1]. Has been used to elucidate the role of BDNF in food intake2, in improvement of cognitive decline during calorie restriction3 and in the discovery of new neurotrophic agents[4].
分子量：407.5
纯度：>98%
