| 产品名称 | TopoGEN | TG1024 | Topoisomerase II Band Shift Kit |
|---|---|
| 目录号 | TG1024 |
| 别名 | Topoisomerase II Band Shift Kit |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| TG1024 | 25 Assays | 咨询 | 咨询 |
TopoGEN | TG1024 | Topoisomerase II Band Shift Kit
品名：Topoisomerase II Band Shift Kit
货号：TG1024
规格：25 Assays
品牌：TopoGEN
产品描述
TopoGEN has extensive experience with assays for topoisomerase inhibition in vivo. This analysis allows the investigator to ascertain whether a novel agent is active against endogenous Top2bin whole cells. An important benefit to this analysis is that one can use any tumor cell or tissue in order to establish clinical efficacy against a specific tumor cell line. We use essentially the same basic approach for Topo I, and Topo IIa,b. The kit is based upon ‘band shifting’ in a western blot using mono-specific antibody probes for Top2a (TG1024-A) or Top2b (TG1024-B. This kit can be used to unambiguously detect a Top2a, or Top2b-specific poisoning in the context of a live cell. It is specific for Top2 poisons and not catalytic inhibitors. In addition, the kit can be used to profile the sensitivity of any given cell line to VP16 or other established Topoisomerase poisons.
