| 产品名称 | TopoGEN | TG2000GSA | Staph aureus DNA Gyrase Enzyme |
|---|---|
| 目录号 | TG2000GSA |
| 别名 | Staph aureus DNA Gyrase Enzyme |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| TG2000GSA | 100 Units; 500 Units; 1000 Units | 咨询 | 咨询 |
TopoGEN | TG2000GSA | Staph aureus DNA Gyrase Enzyme
品名：Staph aureus DNA Gyrase Enzyme
货号：TG2000GSA
规格：100 Units; 500 Units; 1000 Units
品牌：TopoGEN
产品描述
Highly purified Staph aureus DNA gyrase is a type II topoisomerase encoded by two genes GyrA and GyrB from staphylococcus aureus. DNA gyrase is an essential topoisomerase that supercoils DNA through a process of strand breakage/resealing and DNA wrapping. As a type II enzyme, gyrase is unique in its ability to negatively supercoil a relaxed plasmid DNA substrate. S. aureus DNA gyrase is also the target for quinolone-based antibacterial agents which act by subverting the enzyme into a DNA damaging agent. TopoGEN offers purified DNA gyrase from the gram positive bacterium, Staphylococcus aureus for use in all aspects of drug development and screening assays. The enzyme is very active in decatenating and supercoiling kinetoplast DNA (kDNA) but will also negatively supercoil relaxed plasmid DNA. The Staph aureus enzyme is a heterotetramer of GyrA2GyrB2 and is purified as His tagged subunits that are reassembled to make active enzyme.
