| 产品名称 | Synthelis | PL068 | Relaxin receptor 1 |
|---|---|
| 目录号 | PL068 |
| 别名 | RXFP1 |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| PL068 | 10 µg, 50 µg ,100 µg | 咨询 | 咨询 |
Synthelis | PL068 | Relaxin receptor 1
品名：Relaxin receptor 1(RXFP1)
货号：PL068
规格：10 µg, 50 µg ,100 µg
品牌：Synthelis
产品描述
The relaxin/insulin-like family peptide receptor 1 is the cognate receptor for human relaxin-2 in humans. Human RXFP1 also known as LGR7, is located onto the chromosome 4q32.1 and is known to activate Erk1/2, tyrosine kinase(s),gene transcription, and nitric oxide (NO) signaling and can also interact with the glucocorticoid receptor (GC).hRXFP1 is found in a wide range of reproductive tissues including ovary, uterus, placenta, mammary gland, prostate,and testis. The receptor is also present in the heart, kidney, lung, liver and blood cells as well as in several areas of the brain such as cortex, organum vasculosum of the lamina terminalis (OVLT), and subfornical organ (SFO). RXFP1 binds peptide hormones consequently, relaxin not only has autocrine and paracrine roles but also acts as a neuropeptide. It’s a potent chronotropic with inotropic effects on the human heart. Relaxin peptide (RLN) has shown therapeutic effects in an acute heart failure clinical trial.
| Protein | Relaxin receptor 1 |
| Origin | Human |
| Format | Proteoliposome |
| Molecular weight | 89.1 kDa |
| Application | Drug screening & discovery, antibody development, structural biology |
