| 产品名称 | Quartett C-S002/P-S002 | SATB2 (QR023) |
|---|---|
| 目录号 | C-S002/P-S002 |
| 别名 | SATB2 |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：SATB2 (QR023) | Recombinant monoclonal rabbit antibody
货号：C-S002/P-S002
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Nucleus | Control | Colon, colorectal cancer |
| Immunogen | Synthetic peptide from human SATB2 | ||
SATB2 (Special AT-rich sequence-binding protein 2) is a nuclear matrix protein that influences craniofacial formation mechanisms, such as the development of the jaw and palate, and is part of a transcriptional network that regulates skeletal development and osteoblast differentiation. It is highly expressed in the adult and fetal brain and weakly expressed in the liver, kidney, and spinal cord, as well as in some brain regions. SATB2 has been shown to identify colorectal carcinomas, including poorly differentiated colorectal carcinomas and metastases. Adenocarcinomas such as breast, lung, and ovary may express SATB2 at lower frequencies. Therefore, SATB2 is useful for identifying a carcinoma of colorectal origin when a cancer of unknown origin is identified.
