| 产品名称 | Quartett C-M005/P-M005 | MSH6 (QR011) |
|---|---|
| 目录号 | C-M005/P-M005 |
| 别名 | MSH6 |
| 外观 | 见COA |
| 分子量 | |
| CAS | |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
Quartett C-C031/P-C031 | CD31 (QR034)
品名：MSH6 (QR011) | Recombinant monoclonal rabbit antibody
货号：C-M005/P-M005
品牌：Quartett
规格：0.1 ml; 0.5 ml; 1 ml; 3 ml; 7 ml; 15 ml
产品描述
| Application | IHC (FFPE) | Host | Rabbit |
| Subclass | IgG | Dilution range | 1:100 – 1:200 |
| Cellular localization | Cell nucleus | Control | Colon carcinoma, colon mucosa |
| Immunogen | Synthetic peptide from human MSH6 | ||
MSH6, also known as MutS homologue 6, is a key protein in the DNA mismatch repair system. Mutations in the MSH6 gene can lead to microsatellite instability (MSI), which is caused by an accumulation of errors in DNA replication during cell proliferation. MSI is associated with hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome), which is characterized by the development of colorectal cancer, endometrial cancer, and various other tumors at a young age. The MSH6 antibody is useful for the detection of MSI, particularly in a panel with MSH2 (-M004-), PMS2 (-P005-), and MLH1 (-M001-).
