| 产品名称 | Peptides EP08010_1 | CRGDS |
|---|---|
| 目录号 | EP08010_1 |
| 别名 | CRGDS |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| EP08010_1 | 1 mg; 5 mg | 咨询 | 咨询 |
Peptides EP08010_1 | CRGDS
品名：CRGDS
货号：EP08010_1
规格：1 mg; 5 mg
品牌：Peptides.de
产品描述
GRGDS forms the cell-binding domain of a glycoprotein, Osteopontin (OPN) . Although the native form of OPN is active in cell attachment assays, it has been observed that thrombin cleavage of OPN causes substantial enhancement of it's attachment properties. This cleavage occurs within residues of the GRGDS sequence raising the possibility of thrombin-cleavage further activating OPN by allowing greater accessibility of the GRGDS domain to cell surface receptors. GRGDS synthetic peptide also mimics the cellular binding site of many adhesive proteins in the extracellular matrix and causes rounding and detachment of spread cells. It induces dissociation of alpha-actinin and vinculin from the sites of focal contacts.
| Protein | Osteopontin (OPN) |
| Indication | Cell Signaling |
