| 产品名称 | Peptides EP10027_1 | [beta]-Amyloid (1-28) |
|---|---|
| 目录号 | EP10027_1 |
| 别名 | [beta]-Amyloid (1-28) |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| EP10027_1 | 1 mg; 5 mg | 咨询 | 咨询 |
Peptides EP10027_1 | [beta]-Amyloid (1-28)
品名：[beta]-Amyloid (1-28)
货号：EP10027_1
规格：1 mg; 5 mg
品牌：Peptides.de
产品描述
The three-dimensional solution structure of Aß (1-28) reveals the folding of the peptide to form a predominantly a-helical structure with a bend centered at residue 12 and the side chains of histidine-13 and lysine-16 in close proximity, residing on the same face of the helix. Their proximity may constitute a binding motif with the heparan sulfate proteoglycans. Aß (1-28) is highly hydrophilic and shares sequences with bA4, the major component of Aß. Its assembly is fibrillar, i.e., elongated in a single direction. Reports show that synthetic peptides Aß (1-40) and Aß (1-28) have significant effects on normal human plasma cholesterol esterification rate. Both peptides (at concentration of 1 ng/mL) inhibit plasma cholesterol esterification rate by 40-50% compared to the control value.
| Protein | Amyloid-beta precursor protein |
| Species | Human |
| Application | ELISPOT, Flow Cytometry, Western Blotting |
| Indication | Neuroscience |
