| 产品名称 | Peptides EP11075_1 | ABL1 (HLA-A*02:01) |
|---|---|
| 目录号 | EP11075_1 |
| 别名 | ABL1 (HLA-A*02:01) |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| EP11075_1 | 1 mg; 5 mg | 咨询 | 咨询 |
Peptides EP11075_1 | ABL1 (HLA-A*02:01)
品名：ABL1 (HLA-A*02:01)
货号：EP11075_1
规格：1 mg; 5 mg
品牌：Peptides.de
产品描述
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
| Protein | Tyrosine-protein kinase ABL1 |
| Species | Human |
| Application | T-cell stimulation |
| Indication | Cancer |
