| Product Name | Zinc Transporter 8 (ZnT8) Antibody - ELISA |
| Catalog-No. | EA102/96 |
| Description | Enzyme Immuno Assay, for the quantitative determination of autoantibodies to the zinc transporter 8 (ZnT8) in serum |
| Format | 12x8 Determinations, micotiter strips, single break apart |
| Procedure | 25 microlitre calibrators, controls and samples into wells,
18 hrs. incubation, 3 x wash
add ZnT8 biotin, 1h incubation
3 x wash, add SAPOD, 20 min incubation
3 x wash, add substrate. 20 min incubation
stop reaction + read |
| Clinical Fields | Internal medicine, immunology, endocrinology |
| Diseases | Type 1 Diabetes Mellitus (DM) |
| Normal Value | Negative < 15 U/ml; Positive > 15 U/ml |
| Specificity | 97 % ; n = 90 for healthy blood donors (DASP 2015) |
| Sensitivity | 76 %; n = 50 for type 1 DM patients (DASP 2015) |
| Characteristics | Reliable and convenient method to measure specific ZnT8 antibodies which are major component of ICA in type 1 DM and wihich are useful for diagnosis and prediction of type 1 DM. The non-isotopic assy is suitable in routine clinical laboratories in automated or manual formats. |
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