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sRAGE是膜受体RAGE的可溶性形式,可以通过选择性剪接或膜蛋白脱落产生。sRAGE能够与晚期糖基化终末产物等配体结合,但不启动细胞内信号,因此作为诱饵受体发挥作用。在研究中,sRAGE血浆水平常被探讨作为与RAGE信号通路相关的炎症性疾病的生物标志物。

重组人sRAGE蛋白 NebuSelect™ Recombinant Human sRAGE, His-tag
品牌:Nebulabio 货号:NBL-260010 规格:100ug; 500ug; 1mg 别名:可溶性晚期糖基化终末产物受体, Soluble Receptor for Advanced Glycation End-products
产品描述
NebuSelect™重组人可溶性RAGE蛋白(sRAGE),N端带有His标签(产品编号:NBL-260010),采用大肠杆菌表达系统制备。
产品属性
| Target Name | sRAGE | | Appearance | Freeze-dried powder | | Original Concentration | 200µg/mL | | MW | 36.5 kDa | | AA Sequence | 339 aa | | Species | Human | | Expression System | E.coli | | Purity | > 90% | | Alias/Synonyms | Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, SRAGE, RAGE, MGC22357 | | Buffer formulation | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. | | Application | Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.) | | Storage | Avoid repeated freeze/thaw cycles. Store at 2-8℃ for one month. Aliquot and store at -80℃ for 12 months. |
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