维百奥生物代理ubiqbio品牌全系列产品
Ubiqbio创立于2010年，公司总部及实验室位于荷兰阿姆斯特丹科学园，专注于开发、生产基于泛素及泛素样蛋白的科研试剂。我们的技术平台包含三项专有技术：UbiQ-Block™、UbiQ-Click™ 和 UbiQ-Syn™。利用这些化学合成技术，我们可以构建任何泛素缀合物、Ub突变体及其组合。Ubiqbio公司的产品线包括：泛素化肽、活性探针、活性检测试剂、高通量筛选试剂等。
▍ubiqbio技术平台
● UbiQ-Block™
UbiQ-Block™ 技术是一种高效的化学连接方法，使我们能够以位点选择性和天然的方式，构建任何所需的Ub和/或Ub样蛋白（Ubl）修饰的多肽。该技术的核心构件是我们专有的γ-和δ-硫代赖氨酸构建块，这些构建块易于从市售试剂合成，并可用于传统的自动化Fmoc固相肽合成。
应用领域：作为高通量筛选（HTS） assay 试剂，用于寻找去泛素化酶（DUBs）抑制剂；进行DUB活性分析；用于抗体开发；作为基础研究工具。
● UbiQ-Click™
UbiQ-Click™ 技术能够合成明确界定且蛋白酶解稳定的Ub修饰（多）肽。此技术将天然的异肽键替换为蛋白酶解稳定的酰胺等排体。
应用领域：作为惰性结晶工具；用于修饰肽抗原的免疫实验，从而筛选和产生对修饰蛋白/肽具有选择性的抗体；作为基于质谱的蛋白质组学研究的亲和支撑物；用于DUB亲和力研究；作为基础研究工具
● UbiQ-Syn™
UbiQ-Syn™ 是一种新开发的高效线性固相肽全合成技术，用于合成76个氨基酸的Ub多肽序列，能够生产当前生物学方法无法实现的Ub突变体。也可引入亲和标签和荧光染料。
应用领域：研究Ub-蛋白相互作用；研究E1/E2/E3连接机制；作为特殊产品（如放射性标记Ub）的中间体；作为基础研究工具
▍ubiqbio部分产品列表
| 品名 | 货号 | 目录 | 应用 | 规格 |
| Ub-AMC | UbiQ-001 | activity assay reagents | DUB activity profiling, Compound library screening | 100 µg |
| Ub-Rh110Gly | UbiQ-002 | activity assay reagents | DUB activity profiling, Compound library screening | 100 µg |
| TAMRA-Ub | UbiQ-003 | ubiquitin(-like) proteins | Compound library screening | 100 µg |
| K6 linked di-ubiquitin | UbiQ-013 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| K11 linked di-ubiquitin | UbiQ-014 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| K27 linked di-ubiquitin | UbiQ-015 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| K29 linked di-ubiquitin | UbiQ-016 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| K33 linked di-ubiquitin | UbiQ-017 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| NEDD8-FP | UbiQ-019 | activity assay reagents | DUB activity profiling, Compound library screening | 50 µg |
| SUMO1-FP | UbiQ-020 | activity assay reagents | DUB activity profiling, Compound library screening | 50 µg |
| SUMO2-FP | UbiQ-021 | activity assay reagents | DUB activity profiling, Compound library screening | 50 µg |
| 5-TAMRA-Lys-Gly-OH | UbiQ-023 | activity assay reagents | Compound library screening | 25 µg |
| Ub-FANCD2-FP | UbiQ-029 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| K13 Ub-PTEN(5-21)-FP | UbiQ-030 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| K48 linked di-ubiquitin | UbiQ-033 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| K63 linked di-ubiquitin | UbiQ-034 | di-ubiquitin chains | Crystallization, Phenotypic protein profiling | 50 µg |
| Ub-aminoluciferin | UbiQ-036 | activity assay reagents | DUB activity profiling, Compound library screening | 100 µg |
| K119 Ub-H2AX(115-143)-FP | UbiQ-038 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-yH2AX-Ser140(PO4)-FP | UbiQ-039 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| K382 Ub-p53(368-389)-FP | UbiQ-041 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| K382 Ub-p53(357-389)-FP | UbiQ-042 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(1-14)-FP K6 linked | UbiQ-043 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(4-17)-FP K11 linked | UbiQ-044 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(20-33)-FP K27 linked | UbiQ-045 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(22-35)-FP K29 linked | UbiQ-046 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(26-39)-FP K33 linked | UbiQ-047 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(41-54)-FP K48 linked | UbiQ-048 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| Ub-Ub(56-69)-FP K63 linked | UbiQ-049 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
| (Biotin-Ahx-Ub)-(DNP-Ahx-Ub) K48 | UbiQ-056 | activity assay reagents | DUB activity profiling, Compound library screening | 50 µg |
| H2A(113-127) K120Ub | UbiQ-061 | ubiquitinated peptides | Pull down, Western Blot, MS, Target inhibitor profiling | 50 µg |
| linear di-ubiquitin | UbiQ-070 | di-ubiquitin chains | DUB activity profiling | 50 µg |
| ISG15-FP | UbiQ-073 | activity assay reagents | DUB activity profiling, Compound library screening | 50 µg |
| K720 Nedd8-cullin1 (711-730)-FP | UbiQ-080 | activity assay reagents | DUB activity profiling, Compound library screening | 25 µg |
